At least one person is dead after a “major explosion” in Youngstown.

As News Center 7 previously reported, Tuesday around 3:30 p.m. Youngstown’s fire department posted on social media “Please AVOID downtown Youngstown. Major explosion from possible natural gas leak with injuries.”

>> PHOTOS: Several injured after ‘major explosion’ in eastern Ohio

The front of the Realty building on E. Federal Street is damaged and the facade is blown off, according to CBS affiliate WKBN.

Seven people were taken to an area hospital, with one patient in critical condition, a Mercy Health spokesperson confirmed to WKBN.

>> PREVIOUS COVERAGE: 7 injured after ‘major explosion’ in eastern Ohio

Youngstown Fire Chief Barry Finley said there is one person who is unaccounted for.

He later confirmed a second missing person.

Just before midnight Tuesday the coroner was reported on scene of the explosion, according to WKBN.

We will continue to follow this story.