An overnight earthquake killed at least 118 people in a cold and mountainous region in north-western China, the country’s state media reported.

Search and rescue operations were underway in Gansu and neighbouring Qinghai provinces on Tuesday. The earthquake left more than 500 people injured, severely damaged houses and roads, and knocked out power and communication lines, according to media reports.

The magnitude 6.2 earthquake struck near the boundary between the two provinces at a relatively shallow depth of six miles just before midnight on Monday, the China earthquake networks centre said. The US geological survey measured the magnitude at 5.9.

By mid-morning, 105 people had been confirmed dead in Gansu and another 397 injured, including 16 in critical condition, Han Shujun, a spokesperson for the provincial emergency management department said.

Thirteen others were killed and 182 injured in Qinghai in an area north of the epicentre, according to state media.

Another 20 were missing in Qinghai after being buried in a landslide, the China News Service said.

The earthquake was felt in much of the surrounding area, including Lanzhou, the Gansu provincial capital, about 60 miles north-east of the epicentre.

Photos and videos posted by a student at Lanzhou University showed students hastily leaving a dormitory building and standing outside with long down jackets over their pyjamas.

“The earthquake was too intense,” said Wang Xi, the student who posted the images. “My legs went weak, especially when we ran downstairs from the dormitory.”

The quake struck in Gansu’s Jishishan county, about three miles from the provincial boundary with Qinghai.

The epicentre was about 800 miles south-west of Beijing, the Chinese capital. There were nine aftershocks by 10am, about 10 hours after the initial earthquake, the largest one registering a magnitude of 4.1, a Gansu official said.

The remote and mountainous area is home to several predominantly Muslim ethnic groups and near some Tibetan communities.

Tents, folding beds and quilts were being sent to the disaster area, state broadcaster CCTV said. It quoted Chinese leader Xi Jinping as calling for an all-out search and rescue effort to minimize the casualties.

The overnight low in the area was minus 15C to minus 9C , the China meteorological administration said.

At least 4,000 firefighters, soldiers and police officers were dispatched in the rescue effort, and the people’s liberation army western theatre set up a command post to direct its work.

Han, the Gansu spokesperson, said the rescue work was proceeding in an orderly manner and asked people to avoid going to the quake-hit areas to prevent traffic jams that could hinder the effort.

A video posted by the ministry of emergency management showed emergency workers in orange uniforms using rods to try to move heavy pieces of what looked like concrete debris at night.

Other night-time videos distributed by state media showed workers lifting out a victim and helping a slightly stumbling person to walk in an area covered with light snow.

CCTV reported that there was damage to water and electricity lines, as well as transportation and communications infrastructure.

Earthquakes are somewhat common in the mountainous area of western China that rises up to form the eastern edge of the Tibetan plateau.

Last year in September, at least 74 people were reported killed in a 6.8 magnitude earthquake that shook China’s south-western province of Sichuan, triggering landslides and shaking buildings in the provincial capital of Chengdu, where 21 million residents were under a Covid-19 lockdown.

China’s deadliest earthquake in recent years was a 7.9 magnitude quake in 2008 that killed nearly 90,000 people in Sichuan. The tremor devastated towns, schools and rural communities outside Chengdu, leading to a years-long effort to rebuild with more resistant materials.